| Rochester Openings in 2021 | ||
| January 11 | Mercantile on Main | |
| January 11 | Broth | |
| January 11 | Nani's Kitchen | |
| January 11 | Palermo's Market | |
| January 11 | Rococo Coffee Company | |
| January 12 | BBQ Chicken | |
| January 12 | Rancho Viejo | |
| January 18 | Lumos - Culver Road Armory location | |
| January 22 | Body Fuel - Pittsford Plaza location | |
| January 29 | Carmen's Cooking | |
| January 29 | Strangebird Brewery | |
| February | Arthur Jaxson Slice & Scoop -Henrietta location | |
| February | Ortholazer | |
| February | Stem Plants | |
| February 8 | Tai Chi Bubble Tea -Victor location | |
| February 17 | Old Navy -Henrietta location | |
|
