| Rochester closings in 2025 | ||
| Unknown | Smokers Choice - Henrietta and Chili locations | |
| Unknown | Kirkland's | |
| January | Smashburger | |
| January | Stylicious | |
| January 17 | Farmers Creekside Inn | |
| January 25 | Roc Style Chicken & Burger | |
| February | Moe's Southwest Grill - College Town | |
| February 1 | Petit Poutinerie | |
|
