Rochester is home to a number of minor-league professional sports teams, though only one major-league team calls Rochester home.
| Sport | Team | Venue |
| Baseball | Red Wings | Frontier Field |
| Basketball | RazorSharks | Blue Cross Arena |
| Football (Minor League) | Sting | East High School |
| Hockey | Amerks (Americans) | Blue Cross Arena |
| Lacrosse (Indoor) | Knighthawks | Blue Cross Arena |
| Lacrosse (Outdoor) | Rochester Rattlers | Sahlen's Stadium |
| Quad Rugby (Indoor) | WNY Wreckers | |
| Soccer (Outdoor) | Rhinos | Sahlen's Stadium |
| Soccer (Women's Outdoor) | WNY Flash | Sahlen's Stadium |
