Route 33A is relatively short and unlike Route 33, it intersects with I-490 and I-390 only once each. Despite its heavily residential nature, it is a 4 lane road for much of length.
On its western terminus, 33A forks off of 33 south of Bergen at exit 2 on I-490. Its eastern terminus is West Main Street in Rochester, which it forms by merging with West Avenue (33).
In between, it exists as Chili Riga Center Road as it passes through Riga, becoming Chili Avenue at West Chili. The segment in Chili near Paul Road is heavily commercial, including an upscale Wegmans and a KMart. However, it quickly becomes residential again after passing Paul Road. Around Howard Road and Brooks Avenue, it once again becomes commercial, with yet another Wegmans and a Wal-Mart. Past Wegmans, it is once again a residential road.
Business picks up again as it forms exit 19 on I-390, but becomes residential again immediately afterward, with only a few scattered businesses until it meets Thurston Road. Henceforth, the north side of the street is heavily residential, while the south side is largely small business. Rumor has it that Rochester's drug lords keep this section of Chili Avenue free of crime, so as to minimize the police presence. (This rumor should probably be taken with a grain of salt).


